Commercial Strategy & Business Development Associate

Commercial Strategy & Business Development Associate

Proteostasis Therapeutics is an innovative biopharmaceutical company committed to the discovery and development of novel therapeutics to treat diseases caused by an imbalance in the Proteostasis Network (PN). We are driven by the goal of providing new treatment options that offer solutions for all patients, including diseases for which no effective therapies exist. For more information, please visit

We seek to hire talented people and to create an environment that facilitates continued professional growth. The extensive and ongoing work with our founders and collaborators adds an outward-looking, collaborative aspect to the company’s culture. This blend of internal and external talent, combined with cutting-edge science and an innovative business model, make Proteostasis Therapeutics an exceptional place to work.

Position Title: Commercial Strategy & Business Development Associate

Position Overview:

PTI is seeking an Commercial Strategy & Business Development Associate for a full-time position. The candidate will have relevant work experience in the pharmaceutical industry or a demonstrated interest in life sciences. A background in investment banking, consulting, corporate development, or strategy is preferred.

Commercial Strategy Functions:

  • Support the Director of Commercial Strategy & Business Development with the development and execution of commercial strategy for Proteostasis’ pipeline
  • Assist in refining the TPP for CF drug candidates
  • Prepare discussion materials around commercial assumptions and strategy for the Executive Leadership Team and external advisers such as Proteostasis’ Commercial Advisory Board
  • Conduct primary and secondary market research with key stakeholders such as KOLs and payers
  • Identify key commercialization scale up activities and initiate workstreams to support commercial scale up
  • Conduct research on the competitive landscape in CF and propose ways to differentiate Proteostasis’ pipeline
  • Work cross-functionally to identify dependencies and gather key inputs that inform commercial strategy
  • Support development of internal valuation models (rNPV, benchmarks) around product candidates
  • Interact with external vendors and partners to drive commercial strategy

Corporate Development Functions:

  • Support the Director of Commercial Strategy & Business Development and the Executive Leadership Team on corporate development initiatives
  • Help to identify and track interaction with potential commercial partners
  • Analyze and conduct due diligence on potential commercial partners
  • Develop content for financing activities and discussions with investors, investment banks, and research analysts



  • Bachelor’s degree and at least 1 to 2 years of work experience in life sciences, as an analyst in investment banking, consulting, corporate development, or strategy
  • Ability to work in a dynamic and fast-paced environment and to synthesize and distill vast amounts of information quickly
  • Creative and adaptable individual capable of working on multiple workstreams simultaneously
  • Self-starter with strong interpersonal skills and ability to support a lean team
  • Familiarity with excel modeling and valuation concepts preferred
  • Must have strong working knowledge of Microsoft Office applications


Candidates must be authorized to work in the U.S. and live locally only – we will not support relocation for this position. Applicants should send a resume and cover letter to: Director of Human Resources at